Expression of the nm23 gene and breast cancer prognosis.
نویسنده
چکیده
(/) W H D E N PL, PlANTADOSI S, AND THE LUNG CANCER STUDY GROUP: Preoperalive chemotherapy (cisplatin and fluorouracil) and radiation therapy in stage III non-small-cell lung cancer: A phase II study of the Lung Cancer Study Group. JNatl Cancer Inst 83:266-273, 1991 (2) SALMON SE, ED:Adjuvant Therapy of Cancer IV. Philadelphia: Saunders, 1990 (i) ROONEY M, KISH J, JACOBS J, ET AL: Improved complete response rate and survival in advanced head and neck cancer after three-course induction therapy with 120-hour 5-FU infusion and cisplatin. Cancer 55:1123-1128, 1985 (4) SCHULLER DE, METCH B, STEIN DW, ET AL: Preoperative chemotherapy in advanced resectable head and neck cancer. Final report of the Southwest Oncology Group. Laryngoscope 98:1205-1211, 1988 (5) KELSEN DP, MINSKY B, SMITH M, ET AL: Preoperative therapy for esophageal cancer A randomized comparison of chemotherapy versus radiation therapy. JClin Oncol 8:1352-1361, 1990 (6) DILLMAN RO, SEAGREN SL, PROPERT KJ, E T A L A randomized trial of induction chemotherapy plus high-dose radiation versus radiation alone in stage III non-small-cell lung cancer. N Engl J Med 323:940-945, 1990
منابع مشابه
Evaluation of Cytotoxicity Activity and NM23 Gene Expression in T47D Breast Cancer Cell Line Treated with Glycyrrhiza glabra Extract
Glycyrrhiza is a genus of about 20 accepted species in the legume family (Fabaceae), with a distribution in Asia, Australia, Europe, and the Americas. Recently, about 30 species from the genus Glycyrrhiza have been found and used in traditional medicine for treating cancer. Different studies confirmed that down regulation of Non-metastatic protein (NM23), a metastasis suppressor gene is related...
متن کاملEVALUATION OF THE EFFECTS OF IBUPROFEN CYTOTOXIC DOSE ON EXPRESSION LEVEL OF EXTRACELLULAR MATRIX DEGRADING MMP-9 AND ANTI-METASTASIS NM23 GENES IN CERVICAL CANCER CELLS
Background & Aim: Although studies have shown that ibuprofen has anticancer effects on many cancer cells, the mechanism of the ibuprofen anticancer effect in cancer cells is not still well understood. The aim of this study was to investigate the effect of cytotoxic concentration of ibuprofen on the expression level of MMP-9 and NM23 genes in cervical cancer cells. Materials & Methods: During t...
متن کامل[Expressions of vascular endothelial growth factor and nm23-H1 gene and their relation to the prognosis of breast cancer in young women].
OBJECTIVE To investigate the expressions of vascular endothelial growth factor (VEGF) and nm23-H1 gene in breast cancer tissues and their relation to the prognosis in young women. METHODS The expressions of VEGF and nm23-H1 gene were detected using immunohistochemical method (SP) in the breast cancer tissues of 48 young and 30 postmenopausal women with breast cancer and in breast fibroadenoma...
متن کاملEvaluation of PALB2 Gene Expression in Breast Cancer
Breast cancer is the most prevalent malignancy and the second in mortality rate cancers among all cancers in women globally. In Iran it adds up to 16 percent of all cancers and is the most prevalent cancer in Iranian women. PALB2, identified as a partner and localizer of BRCA2 and proposed to have some roles in DNA damage response, has recently been identified as a breast canc...
متن کاملClinical significance of nm23 expression in resected pathologic-stage I, non-small cell lung cancer.
BACKGROUND Clinical significance of the status of nm23 gene, originally identified as an antimetastatic gene, in non-small cell lung cancer remains unestablished, whereas many clinical studies have demonstrated that reduced nm23 expression is correlated with tumor progression and poor prognosis in a variety of malignant tumors such as breast carcinoma. METHODS nm23 expression was examined imm...
متن کاملIdentification of Prognostic Genes in Her2-enriched Breast Cancer by Gene Co-Expression Net-work Analysis
Introduction: HER2-enriched subtype of breast cancer has a worse prognosis than luminal subtypes. Recently, the discovery of targeted therapies in other groups of breast cancer has increased patient survival. The aim of this study was to identify genes that affect the overall survival of this group of patients based on a systems biology approach. Methods: Gene expression data and clinical infor...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of the National Cancer Institute
دوره 83 4 شماره
صفحات -
تاریخ انتشار 1991